Protein Details: Glutamate receptor 1.1

Protein ID

ICDB_Pro_1563

Protein Name

Glutamate receptor 1.1

Gene Name

GLR1.1; GLR1; At3g04110; T6K12.27

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

808 amino acids

AlphaFoldDB

AF-Q9M8W7-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. Can transport sodium; potassium; and calcium ions. Functions as a carbon and nitrogen regulator and/or sensor that regulates carbon and nitrogen metabolism and distinct physiological process such as germination through the control of acid abscisic (ABA) biosynthesis. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Seems required for the regulation of the abscisic acid (ABA) signaling pathway that modulates many aspects of plant physiology such as seed germination and response to drought (e.g. stomata opening).

Sequence

MEILFSISILALLFSGVVAAPSDDDVFEEVRVGLVVDLSSIQGKILETSFNLALSDFYGINNGYRTRVSVLVRDSQGDPIIALAAATDLLKNAKAEAIVGAQSLQEAKLLATISEKAKVPVISTFLPNTLSLKKYDNFIQWTHDTTSEAKGITSLIQDFSCKSVVVIYEDADDWSESLQILVENFQDKGIYIARSASFAVSSSGENHMMNQLRKLKVSRASVFVVHMSEILVSRLFQCVEKLGLMEEAFAWILTARTMNYLEHFAITRSMQGVIGFKSYIPVSEEVKNFTSRLRKRMGDDTETEHSSVIIGLRAHDIACILANAVEKFSVSGKVEASSNVSADLLDTIRHSRFKGLSGDIQISDNKFISETFEIVNIGREKQRRIGLWSGGSFSQRRQIVWPGRSRKIPRHRVLAEKGEKKVLRVLVTAGNKVPHLVSVRPDPETGVNTVSGFCVEVFKTCIAPFNYELEFIPYRGNNDNLAYLLSTQRDKYDAAVGDITITSNRSLYVDFTLPYTDIGIGILTVKKKSQGMWTFFDPFEKSLWLASGAFFVLTGIVVWLVERSVNPEFQGSWGQQLSMMLWFGFSTIVFAHREKLQKMSSRFLVIVWVFVVLILTSSYSANLTSTKTISRMQLNHQMVFGGSTTSMTAKLGSINAVEAYAQLLRDGTLNHVINEIPYLSILIGNYPNDFVMTDRVTNTNGFGFMFQKGSDLVPKVSREIAKLRSLGMLKDMEKKWFQKLDSLNVHSNTEEVASTNDDDEASKRFTFRELRGLFIIAGAAHVLVLALHLFHTRQEVSRLCTKLQSFYK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in roots. First detected in the root-shoot junction; and later in lateral roots and at the margin of matures leaves.

DOI ID

10.1038/24066; 10.1038/35048706; 10.1111/tpj.13415; 10.1126/science.1071006; 10.1126/science.292.5521.1486b; 10.1093/oxfordjournals.molbev.a004165; 10.1073/pnas.1030961100; 10.1093/pcp/pch159; 10.1016/j.jmb.2008.06.076

RefSeq

NP_187061.1

Feature